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Frontiers | Diversity of Nuclear Lamin A/C Action as a Key to Tissue-Specific Regulation of Cellular Identity in Health and Disease
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Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes - ScienceDirect
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LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation - ScienceDirect
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A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization | PNAS
Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation | PLOS ONE
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The structural and gene expression hypotheses in laminopathic diseases—not so different after all | Molecular Biology of the Cell
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Increased expression of the Hutchinson–Gilford progeria syndrome truncated lamin A transcript during cell aging | European Journal of Human Genetics
David R. Liu on Twitter: "The mutation (discovered by @NIHDirector's lab in 2003) results in progerin, a toxic protein that damages nuclei. So providing more healthy LMNA is not a solution, and
![Frontiers | The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype Frontiers | The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype](https://www.frontiersin.org/files/MyHome%20Article%20Library/538082/538082_Thumb_400.jpg)
Frontiers | The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype
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Lamin A/C protein (top), gene structure (middle), and localization of... | Download Scientific Diagram
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Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria - ScienceDirect
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Role of nuclear Lamin A/C in cardiomyocyte functions - Carmosino - 2014 - Biology of the Cell - Wiley Online Library
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A novel LMNA mutation (R189W) in familial dilated cardiomyopathy: evidence for a 'hot spot' region at exon 3: a case report | Cardiovascular Ultrasound | Full Text
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Comparison of lamin A, lamin C, and LA ⌬ 50 structures. ( A ) The 12... | Download Scientific Diagram
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